英文药名:Anastrozole tab(Anastrozole)
中文药名:阿那曲唑片
生产厂家:卫材和化药
アナストロゾール錠1mg
治疗类别名称
芳香酶抑制剂/绝经后乳腺癌的治疗剂
商標名
Anastrozole tab.
一般 名
アナストロゾール(Anastrozole)
化 学 名
2-[3-(1-Cyano-1-methylethyl)-5-(1H-1, 2, 4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile
分 子 式
C17H19N5
分 子 量
293.37
構 造 式
物理化学的性状
阿那曲唑是一种白色粉末。
它非常易溶于乙腈和易溶于(99.5)N,N-二甲基甲酰胺,甲醇,乙醇,和极微溶于水的这篇文章。
使用注意事项
*长期测试
结果(25℃,60%相对湿度,36个月)的长期测试中,阿那曲唑片1mg的(最后的包装),是稳定在正常的市场流通三年被证实)
适应症
绝经后的乳腺癌
剂量和用法
成人每天一次,口服给药于1mg。
包装规格
片剂
1mg:30片(PTP)100片(PTP)
* 制造厂商
Erumeddo卫材有限公司
1mg:10片(10片×1),30片(10片×3),100片(10片×10)
* 制造厂商
日本化药有限公司
注:使用以原处方为准:
1):http://www.info.pmda.go.jp/go/pack/4291010F1040_1_02/
2):http://di-pedia.com:808/DIC_GOOCO/Attach/4291010F1090_1_04.html
Arimidex lowers estrogen levels in postmenopausal women to slow the growth of certain cancer tumors. It works inhibiting enzyme aromatase and hereby production of estrogen.
Dosage and direction
Follow all instructions of your doctor about treatment and dosing schedule. Do not take more of this medication than it was administered to you. Take once daily.
Precautions
Inform your doctor if you are pregnant or breastfeeding, a severe liver disease, history of stroke of blood clot, heart disease, circulation problems, or if you have not yet completed menopause. If you have such conditions you may need adjustment of your dose. Your treatment with Arimidex may continue for five years. This medication may impair your ability to high concentration of attention and thinking or reactions: be especially careful while driving or operating machinery.
Contraindications
Do not use Arimidex in premenopausal women, in pregnant and breastfeeding women, severe kidney disorders, moderate and severe liver diseases, hypersensitivity to Arimidex or other components of the drug. Preparations which contain estrogens should not be administered with Arimidex as they neutralize its pharmacological effect.
Side effects
The most frequent side effects include sings of allergy (hives, skin rash, facial swelling and difficulty breathing) together with sudden headache, confusion, problems with vision, speech, or balance, sudden numbness or weakness, especially on one side of the body, a bone fracture, swollen glands, swelling in your hands or feet. Rare and not so serious adverse reactions such as hot flashes, sore throat, weakness, back pain, bone pain, nausea are also possible.
Drug interaction
Inform your doctor if you take tamoxifen or estrogen. Inform your doctor about all prescribed and over -the-counter medications, herbal products, vitamins and food supplements you use.
Missed dose
If you missed a dose take it as soon as you remember. If it almost time of your next dose just skip it and return to your regular schedule. Never double dose this medication.
Overdose
There is not information about Arimidex overdose. If you suspect that you took too much of this medication contact your doctor immediately.
Storage
Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.