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L-Cartin FF oral solution10%(左卡尼汀FF口服液)

2015-05-15 10:46:19  作者:新特药房  来源:互联网  浏览次数:187  文字大小:【】【】【
简介: 英文药名:L-Cartin FF oral solution(Levocarnitine) 中文药名:左卡尼汀FF口服液 日文药名:エルカルチンFF内用液10% 生产厂家:大冢制药药品介绍类别名称左旋肉碱配方商標名 L-Cartin FF ora ...

英文药名:L-Cartin FF oral solution(Levocarnitine)

中文药名:左卡尼汀FF口服液

生产厂家:大冢制药

エルカルチンFF内用液10%

类别名称
左旋肉碱配方
商標名
L-Cartin FF oral solution 10%
一般名
レボカルニチン〔Levocarnitine(JAN)〕
化学名
(R)-3-Hydroxy-4-trimethylammoniobutanoate
構造式

分子式
C7H15NO3
分子量
161.20
性状
它是一种白色结晶粉末。这是非常易溶于水,微溶于乙醇(99.5)。它是吸湿的。的水溶液(1→20)的PH值是6.5至8.5。
操作注意事项
被存储在一个地方让儿童接触不到的地方
药理作用
本品是哺乳动物能量代谢中的必需物质,其主要功能是促进脂类代谢,可以使缺血、缺氧时堆积的脂酰辅酶A进入线粒体内,减少其对腺嘌呤核苷酸转位酶的抑制,使氧化磷酸化得以顺利进行。
本品静注还可以纠正血液透析患者体内卡尼汀的缺乏,改善营养状态和因卡尼汀缺乏引起的一系列并发症。
本品能加速正常心肌脂肪酸的氧化,为心肌ATP提供来源;降低乙酰辅酶A与游离辅酶A的比例,调节丙酮酸的氧化使葡萄糖氧化增加;减轻心脏缺血损伤程度,促进再灌注时心功能恢复,提高运动耐力。
此外,本品还能增加NADH细胞色素C还原酶和细胞色素氧化酶的活性、参与某些药物的解毒作用,有效对抗蒽环类及其他抗肿瘤药物的心脏毒性。
适应证
左卡尼汀是一种用途广泛的氨基酸类药物,加本品替补疗法用于长期的血液透析、左卡尼汀缺乏症、肌肉营养不良、心肌病、急性和慢性心肌梗塞形成、心绞痛、三环类抗抑郁药引起的心律失常、老年性痴呆症、早老性痴呆以及机能衰弱。
用法用量
成人;划分口服给药1日1.5-3g处(15-30毫升),以3倍。该剂量可以适当地调整根据患者的病情。
儿童;划分口服25-100毫克的(0.25-1毫升),每天千克体重用3次。该剂量可以适当地调整根据患者的病情。
<参考>
此药等同于氯化左旋肉碱(Erukaruchin片)1,800mg在15毫升(左卡尼汀1.5克)。
包装规格
FF口服液10%:10毫升×10瓶


生产商:
大冢制药有限公司
L-Cartin FF oral solution(Levocarnitine)エルカルチンFF内用液10%
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name : L-CARTIN FF Oral Solution 10%
 Active ingredient: Levocarnitine
 Dosage form: colorless to slightly yellow, clear solution
 Print on wrapping: 
Effects of this medicine
This medicine activates mitochondrial function by improving a carnitine deficient state, and improves symptoms such as convulsive attack and hypotonia.
It is usually used for the treatment of carnitine deficiency.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have renal disorder.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•In general, for adults, take 15 to 30 mL (1.5 to 3 g of active ingredient) daily, in 3 divided doses. For children, take 0.25 to 1 mL (25 to 100 mg of active ingredient)/kg of body weight daily, in 3 divided doses. The dosage may be adjusted according to your symptoms. This preparation contains 10 mL (1 g of active ingredient) per bottle. Strictly follow the instructions of your doctor and pharmacist.
•If you miss a dose, take the dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
•If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
•Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
• Possible adverse reactions to this medicine
The most commonly reported adverse reactions include loss of appetite, diarrhea, loose stools, enlarged feeling of abdomen, facial edema, hematuria, and anemia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
No pertinent entries.
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Keep out of the reach of children. Store away from direct sunlight, heat and humidity.
•If there is a remainder, this is to be discarded. Do not store it.
Otsuka Pharmaceutical Co., Ltd.Internal
Published: 3/2013
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
http://www.kegg.jp/medicus-bin/japic_med?japic_code=00061227
http://www.info.pmda.go.jp/go/pack/3999033S1024_1_04/

责任编辑:admin


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