英文药名：Ciloslet Oral Jelly（Cilostazol） 中文药名：西洛他唑口腔果冻 生产厂家：Nichi-IKO药业 シロスレット内服ゼリー50mg／シロスレット内服ゼリー100mg 治疗类别名称 抗血小板剂 批准日期：2012年11月 欧文商標名 Ciloslet 一般名 シロスタゾール（Cilostazol） 化学名 6-[4-(1-Cyclohexyl-1H -tetrazol-5-yl)butyloxy]-3,4-dihydroquinolin-2(1H )-one 化学構造式： 分子式 C20H27N5O2 分子量 369.46 性状 白细黄白色晶体或结晶性粉末。 甲醇，乙醇（99.5），或微溶于乙腈，和几乎不溶于水。 熔点 158〜162℃ 适应病症 ・ 基于慢性动脉闭塞性疾病的溃疡，改善疼痛和冷感等缺血症状 ・ 脑梗塞（不包括心源性脑栓塞）发病后抑制复发 用法用量 成人，每日口服二次 每次100毫克。该剂量可以根据年龄和症状进行调整。 包装规格 口服果冻： 50毫克  100包 100毫克 100包 制造厂商 Nichi-IKO公司 Ciloslet Oral Jelly（Cilostazol） Ciloslet Oral Jelly 50mg（シロスレット内服ゼリー50mg）  Brand name : Ciloslet Oral Jelly 50mg 　Active ingredient: Cilostazol 　Dosage form: white to slightly yellowish white jelly 　Print on wrapping: シロスレット内服ゼリー50mg,NICHI-IKO Ciloslet Oral Jelly 100mg（シロスレット内服ゼリー100mg）  Brand name : Ciloslet Oral Jelly 100mg 　Active ingredient: Cilostazol 　Dosage form: white to slightly yellowish white jelly 　Print on wrapping: シロスレット内服ゼリー100mg,NICHI-IKO Effects of this medicine This medicine inhibits platelet aggregation caused by thromboxane A2, etc. to prevent blood coagulation. It also suppresses thrombus formation by antiplatelet action and improves blood flow by vasodilation. It is usually used to improve ischemic symptoms such as ulcer, pain and chilly sensation caused by chronic arterial occlusion, and prevent recurrence of cerebral infarction (except for cardiogenic embolism) after its event. Before using this medicine, be sure to tell your doctor and pharmacist •If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines. If you are bleeding (hemophilia, capillary fragility, intracranial hemorrhage, gastrointestinal bleeding, urinary tract bleeding, hemoptysis, vitreous hemorrhage, etc.). If you have congestive heart failure or a plan for surgery or tooth extraction. •If you are pregnant, possibly pregnant or breastfeeding •If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.) Dosing schedule (How to take this medicine) •Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>> •In general, for adults, take 2 packets (100mg of the active ingredient) at a time, 2 times a day. The dosage may be adjusted according to disease, age and symptoms of the patient. Strictly follow the instructions. •Open the packet and take the contents only. •Read the instruction, <患者さんへ (For the patients)>, about the way to open the packet (This instruction is written only in Japanese). Take this medicine immediately after opening the packet and discard the liquid left in the packet. DO NOT take this medicine besides oral administration. •If you miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time. •If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist. •Do not stop taking this medicine unless your doctor instructs you to do so. Precautions while taking this medicine •Do not take grapefruit juice and the medicine together as the components of it may intensify the effect of the medicine. •In case of bleeding, blood may not clot quickly. If bleeding time is prolonged or the injury involves a large area, immediately visit the hospital. •Be sure to tell your doctor that you are taking this medicine if you undergo surgery or dental treatment. Possible adverse reactions to this medicine The most commonly reported adverse reactions include rash, skin rash, hives, itch, photosensitivity, erythema, palpitation, frequent pulse, glow, headache, dull headache, dizziness, insomnia, numbness, sleepiness, tremor, stiff shoulder, faint/transient loss of consciousness, abdominal pain, nausea/vomiting and diarrhea. If any of these symptoms occur, consult with your doctor or pharmacist. The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately. •respiratory distress, acute sensation of pressure/constriction in the chest, chest pain [congestive heart failure, myocardial infarction, angina pectoris, ventricular tachycardia] •headache, impaired consciousness, abdominal pain [bleeding (intracranial hemorrhage such as cerebral hemorrhage, pulmonary hemorrhage, gastrointestinal bleeding, nasal bleeding, fundal hemorrhage, etc.)] •pain in the pit of the stomach, tenderness, nausea [gastric/duodenal ulcer] •sore throat, headache, nasal/gum bleeding  [pancytopenia, agranulocytosis, thrombocytopenia] •fever, dry cough, respiratory distress [interstitial pneumonia] The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above. Storage conditions and other information •Keep out of the reach of children. Store away from direct sunlight, heat and moisture. •Discard the remainder. Do not store them. Nichi-iko Pharmaceutical Co.,LtdInternal Published: 3/2013 The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment. 原处方附件：http://www.info.pmda.go.jp/go/pack/3399002Q1029_5_01/