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当前位置:药品说明书与价格首页 >> 肝病 >> 新药推荐 >> Neophagen C combination tablet(甘草酸单铵/甘氨酸/DL-蛋氨酸组合片)

Neophagen C combination tablet(甘草酸单铵/甘氨酸/DL-蛋氨酸组合片)

2017-03-15 09:51:16  作者:新特药房  来源:互联网  浏览次数:2  文字大小:【】【】【
简介: 英文药名:Neophagen C combination tablet(Monoammonium Glycyrrhizinate/Glycine/DL-Methionine) 中文药名:甘草酸单铵/甘氨酸/DL-蛋氨酸组合片 生产厂家:大鹏药业 ネオファーゲンC配合錠 治疗 ...

英文药名:Neophagen C combination tablet(Monoammonium Glycyrrhizinate/Glycine/DL-Methionine)

中文药名:甘草酸单铵/甘氨酸/DL-蛋氨酸组合片

生产厂家:大鹏药业

ネオファーゲンC配合錠

治疗类别名称
抗病毒,抗过敏,肝病
商標名
Neophagen C combination tablet
组成
成分含量(1片)
甘草酸单铵酸(甘草甜素酸)25mg
甘氨酸为25mg
DL-蛋氨酸为25mg
药效药理
甘草甜素酸甘草甜味成分是,已被用来作为自古以来的药物的草本植物,还,它也是一个主要成分,具有解毒,抗过敏作用,抗炎症作用,肝功能衰竭的恢复操作等。
甘氨酸参与生理学重要肌酸,谷胱甘肽,卟啉,布丁的物质的生物合成等,具有解毒作用。
蛋氨酸是一种必需氨基酸,是蛋白质的组成部分,通过三磷酸腺苷体内活化以及涉及甲基化在体内,半胱氨酸和胱氨酸的SH基团供体中起着重要作用的药物和生物成分是生物合成,发挥解毒作用。
适应病症
○湿疹,皮炎,儿童strophulus,斑秃,口腔炎
○慢性肝病异常,肝功能的改善
用法与用量
成人:每日一次,每次2-3片。儿童,每日三次,每次1片。此外,增加或减少取决于患者的年龄和症状。
包装规格
PTP包装:1000片(10片×100)瓶包装:2000片


完整资料附件:http://www.info.pmda.go.jp/go/pack/3919100F1177_1_04/


Name of drug classification
Antiallergic·liver disease agents
Sales name
Neophagen C compounding tablets
Glycyrrhizinate monoammonium
common name
Glycyrrhizinate monoammonium
(Monoammonium Glycyrrhizinate)
Chemical name
Monoammonium of 20 β-carboxy-11-oxo-30-norolean-12-en -3β-yl-2-O-β-D-glucopyranuronosyl-α-D-glucopyranosiduronic acid
Molecular formula
C42 H61 O 16 NH 4
Molecular weight
839.96
Property
It is a white to slightly yellow crystalline powder, it has no odor and has a unique sweetness. It is difficult to dissolve in water and ethanol (99.5), and it is hardly soluble in chloroform or diethyl ether.
Glycine(aminoacetic acid)
common name
glycine
(Glycine)
Chemical name
Aminoacetic acid
Molecular formula
C2 H 5 NO 2
Molecular weight
75.07
Property
It is white crystal or crystalline powder, it has no odor and taste sweet. It is easily soluble in water or formic acid and hardly soluble in ethanol (95).
DL-methionine
common name
DL-methionine
(DL-Methionine)
Chemical name
(2RS) -2-Amino-4- (methylsulfanyl) butanoic acid
Molecular formula
C 5 H 11 NO 2 S
Molecular weight
149.21
Property
White crystal or crystalline powder, has a unique odor and taste slightly sweeter. It is slightly soluble in water, is very insoluble in ethanol (95), and hardly soluble in diethyl ether. It is soluble in dilute hydrochloric acid or sodium hydroxide solution.
The pH of the aqueous solution (1 → 100) is 5.6 to 6.1. The aqueous solution (1 → 100) has no optical rotatory power.
Sales name
Neophagen C compounding tablets
composition
Component Content
In 1 tablet
Ammonium glycyrrhizinate (as glycyrrhizic acid) 25mg
Glycine 25mg
DL-Methionine 25mg
Additive
Precipitated calcium carbonate, low substituted hydroxypropyl cellulose, hypromellose, crystalline cellulose, carmellose sodium, magnesium stearate, titanium oxide, Macrogol 6000
Contraindications
Patients with end-stage cirrhosis with an elevated serum ammonium level [metabolites of DL-methionine contained in this drug suppresses urea synthesis and may lower ammonia treatment capacity]
Patients with aldosteronism, myopathy, hypokalemia [There is a risk of deteriorating hypokalemia, hypertension, etc]
Indication or effect
Eczema/dermatitis, childhood strofuls, alopecia areata, stomatitis
Improvement of abnormal liver function in chronic liver disease
Usually, 2 to 3 tablets once for adults and 1 tablet for children are orally administered three times a day after meals.
Incidentally, it should be increased or decreased according to your age and symptoms.
Careful Administration
Elderly people [The incidence of hypokalemia etc. is high] (See "Administration to the Elderly" section)
Serious side effects
[Frequency of expression unknown]
Pseudoaldosteronism
Pseudoaldosteronism such as hypokalemia, elevated blood pressure, sodium/body fluid storage, edema, urine volume reduction, body weight gain, etc. may appear, so observe (measurement of serum potassium level etc.) thoroughly, If you are admitted, discontinue administration.
In addition, symptoms of rhabdomyolysis, such as weakness, muscle weakness, muscle pain, limbs convulsions/paralysis, etc. may occur, so if CK (CPK) elevation, elevation of myoglobin in blood and urine is observed Discontinue administration and take appropriate measures.
Medicinal pharmacology
Glycyrrhizic acid is a sweet component of licorice which has been used as medicine for a long time and is also a main ingredient and has detoxification action, antiallergic action, anti-inflammatory action, hepatic disorder recovery action and the like.
Glycine is involved in biosynthesis of physiologically important substances such as creatine, glutathione, porphyrin, purine and the like, and has detoxifying action.
Methionine is an essential amino acid, a constituent of a protein, which is activated by ATP in vivo and is involved in methylation of drugs and biological components that play an important role in vivo, and as a SH group donor, cysteine and cystine Biosynthesize and exert detoxification action.

责任编辑:p53


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