【药品名称】克拉屈滨注射液
【英文或拉丁名】Cladribine Injection 【化学名】2-氯-6-氨基-9-(2-脱氧-β-D-赤型-呋喃戊糖基)嘌呤 【性状】本品为无色或几乎无色的澄明液体。 【药理毒理】 【药代动力学】 【临床研究】 【适应症】本品可试用于经干扰素治疗失败后活动性的伴有临床意义的贫血、中性粒细胞减少、血少板减少以及疾病相关症状的毛细胞白血病(HCL)治疗。 【用法与用量】静脉滴注。治疗多毛细胞白血病时的建议剂量为克拉屈滨0.09mg/kg/d,作24小时的连续滴注,连用7天。不推荐其它的用药方案。根据己有经验,如患者对初始疗程无效,增加疗程不会获得更大利益。临用前按计算量。 【原产地英文商品名】LEUSTATIN 1mg/ml 10mls/vial 【贮藏】2-8度冷藏。 ---------------------------------------------------------------- What is cladribine (Cladribine Novaplus, Leustatin)? Cladribine is used to treat a type of blood cancer (Hairy Cell Leukemia). Cladribine may also be used for purposes other than those listed in this medication guide. ---------------------------------------------------------------- What are the possible side effects of cladribine (Cladribine Novaplus, Leustatin)? If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately: Other less serious side effects may be more likely to occur. Talk to your doctor if you experience: ---------------------------------------------------------------- What is the most important information I should know about cladribine (Cladribine Novaplus, Leustatin)? Serious side effects have been reported with the use of cladribine including: allergic reactions (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; fever or chills; or signs of infection such as fever; chills, or sore throat); neurologic problems; kidney problems; and others. Talk to your doctor about the possible side effects from treatment with cladribine. ---------------------------------------------------------------- Who should not take cladribine (Cladribine Novaplus, Leustatin)? Cladribine is in the FDA pregnancy category D. This means that cladribine is known to cause birth defects in an unborn baby.Do not take cladribine without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether cladribine passes into breast milk. Do not take cladribine without first talking to your doctor if you are breast feeding a baby. ---------------------------------------------------------------- How should I use cladribine (Cladribine Novaplus, Leustatin)? Your doctor will determine the correct amount and frequency of treatment with cladribine depending upon the type of cancer being treated and other factors. Talk to your doctor if you have any questions or concerns regarding the treatment schedule. Your doctor will probably want you to have regularly scheduled blood tests and other medical evaluations during treatment with cladribine to monitor progress and side effects. Skin accidentally exposed to cladribine should be rinsed thoroughly with soap and warm water. Your healthcare provider will store cladribine as directed by the manufacturer. If you are storing cladribine, follow the directions provided by your healthcare provider. ---------------------------------------------------------------- What happens if I miss a dose (Cladribine Novaplus, Leustatin)? ---------------------------------------------------------------- What happens if I overdose (Cladribine Novaplus, Leustatin)? Symptoms of a cladribine overdose tend to be similar to side effects caused by the medication, although often more severe. ---------------------------------------------------------------- What should I avoid while taking cladribine (Cladribine Novaplus, Leustatin)? Skin accidentally exposed to cladribine injection should be rinsed thoroughly with soap and warm water. ---------------------------------------------------------------- What other drugs will affect cladribine (Cladribine Novaplus, Leustatin)? Other medications may interact with cladribine. Talk to your doctor and pharmacist before taking any other prescription or over-the-counter medicines, including herbal products, during treatment with cladribine. ---------------------------------------------------------------- Where can I get more information? Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. |
克拉屈滨注射剂|LEUSTATIN(CLADRIBINE)简介:
【药品名称】克拉屈滨注射液
【英文或拉丁名】Cladribine Injection
【化学名】2-氯-6-氨基-9-(2-脱氧-β-D-赤型-呋喃戊糖基)嘌呤
【性状】本品为无色或几乎无色的澄明液体。
【药理毒理】药理作用: ... 责任编辑:admin |
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