英文名称：Warfarin Granules 0.2%（Warfarin Potassium）

中文名称：华法令钾顆粒0.2％

生产厂家：卫材制药

ワーファリン顆粒0.2％

治疗类别名称
口服抗凝
商標名
Warfarin
一 般 名
ワルファリンカリウム（Warfarin Potassium）
化 学 名
Monopotassium（1RS）-2-oxo-3-（3-oxo-1-phenylbutyl）chromen-4-olate
分 子 式
C19H15KO4
分 子 量
346.42
構 造 式

物理化学性质
华法林钾是一种白色的结晶性粉末。
它是非常易溶于水，易溶于乙醇（95）。
该产品是易溶于氢氧化钠TS。
该溶液的pH值，溶解在100mL水中，1.0g的此产品是7.2至8.3。
本产品是一种浅黄色的光。
不显示旋光度（1→10）本产品的水溶液。
操作注意事项
本剂白色沉积物的颗粒的表面上观察到的是通过添加剂。
适应病症
治疗和预防（如脑血栓，进行静脉血栓形成，心肌梗死，肺栓塞，脑栓塞，慢慢地）血栓栓塞
用法与用量
此药为基础的药物测试，以确定剂量的这种药物测试凝血（凝血酶原时间和Toronbotesuto），同时彻底管理血液凝固的价值。
调整后的剂量口服给药的初始剂量，每天一次，治疗范围凝血超过数天的测试，以确定的维持剂量。
由于个体差异大的变化，同一个人在华法林的敏感性，凝血试验，可以进行必要的定期调整维持剂量。
抗凝血作用，考虑到剂量的组合，如肝素。
成人：初始剂量通常为每天一次，1〜5mg1。
儿童：维持剂量。
12ヵ月未満0.16mg/kg/
1歳以上15歳未満：0.04〜0.10mg/kg/
包装规格
ワーファリン顆粒0.2％：100g

生产商：卫材制药
完整处方附件：http://www.info.pmda.go.jp/go/pack/3332001D1023_1_05/
Warfarin Granules0.2%（ワーファリン顆粒0.2%）
Brand name : Warfarin Granules0.2%
　Active ingredient: Warfarin potassium
　Dosage form: dark red granules
　Print on wrapping: 
Oral anti-coagulant "0.2% warfarin granules" new released in Japan
Eisai Co., Ltd. (Headquarters: Tokyo, President and CEO: Haruo Naito) is, December 1, in Japan, an oral anti-coagulant "warfarin" (generic name: warfarin potassium) becomes a new dosage form of "0.2% warfarin granules" the then new release.
This drug is, difficult patient is taking the tablets also can be taken, as a preparation that is capable of performing the trace adjustment of the dose, received an approval of production and marketing in this year July 15, November 28, It has been NHI price listing to.
We will continue to contribute to the improvement.
"Warfarin" is an oral anticoagulant that has a wide range of indications and effects, its usefulness in large-scale clinical trials in overseas has been demonstrated. In particular, cardiogenic cerebral embolism, in the treatment and prevention of thromboembolic diseases such as venous thrombosis, in Japan, the United States and Europe of clinical practice guidelines has become the first drug of choice, it has been prescribed to many patients. On the other hand, "Warfarin" has a narrow therapeutic range, it is known that the interaction is often with other agents, by the monitoring of blood clotting ability of measurement, such as prothrombin time, is a drug that requires adjustment of the dose.
This time the new release "0.2 percent Warfarin granules" is available for difficult patients like taking tablets such as swallowing difficulties and children, it has become a small amount of regulation can also be formulated. This drug, while it possible to adjust the precise 0.5mg following trace warfarin potassium as the component sets the diffuser 500 times to ensure the appropriate amount of dose volume. Although warfarin potassium has the property of gradually decomposed by light, the agent, by performing the contrivance such as coated granules, making it a formulation with enhanced light stability.
The Company, "warfarin" has been estimated to have been administered to currently about 100 million people of the patients in Japan. This time, the existing warfarin tablets 0.5mg, 1mg, new by adding the granules to 5mg, more and more patients benefit