英文药名：ENCRUSE ELLIPTA(Umeclidinium Bromide)

中文药名：芜地溴铵长效吸入剂

生产厂家：葛兰素史克公司
治疗类别名称
长效吸入支气管扩张剂
商標名
ENCRUSE 62.5μg ELLIPTA
一般名
ウメクリジニウム臭化物（Umeclidinium Bromide）
化学名
1-［2-（Benzyloxy）ethyl］-4-（hydroxydiphenylmethyl）-1-azoniabicyclo［2.2.2］octane bromide
分子式
C29H34BrNO2
分子量
508.49
構造式

性状
它是一种白色粉末。
操作注意事项
（1）用于传递对患者使用的指示，被指示如何使用。
（2）本药物，因为它是铝包装防潮，它们被指示只是使用开始之前打开铝包装。
审批条件
在制定药品风险管理计划，正确实施的。
药效药理
UMEC是一种长效选择性毒蕈碱受体拮抗剂，我告诉所有的毒蕈碱受体亚型具有高亲和力（M1〜M5受体）。 UMEC抑制由竞争性支气管平滑肌收缩抑制乙酰胆碱的结合存在于支气管平滑肌毒蕈碱受体。作用在体外对UMEC的M3受体显示出缓慢恢复，由单一气管内施用UMEC的豚鼠，表明长效对抗乙酰胆碱诱发的支气管收缩的抑制效果。
适应病症
基于慢性阻塞性肺疾病的呼吸道阻塞症状缓解（慢性支气管炎，肺气肿）
用法用量
通常情况下，成人每天一次吸入62.5μg管理。
包装规格
62.5μg Eriputa 7吸入×1
62.5μg Eriputa 30吸入×1

制造商（进口）
日本葛兰素史克公司

注：以上中文仅供参考，使用以原资料为准！
http://www.info.pmda.go.jp/go/pack/2259714G1028_1_04/
ENCRUSE 62.5μg ELLIPTA(Umeclidinium Bromide)

Encruse 62.5µg Ellipta 7 doses（エンクラッセ62.5μgエリプタ7吸入用） 
Brand name : Encruse 62.5µg Ellipta 7 doses
　Active ingredient: Umeclidinium Bromide
　Dosage form: Dry powder inhaler
　Print on wrapping
Encruse 62.5µg Ellipta 30 doses（エンクラッセ62.5μgエリプタ30吸入用）
Brand name : Encruse 62.5µg Ellipta 30 doses
　Active ingredient: Umeclidinium Bromide
　Dosage form: Dry powder inhaler
　Print on wrapping: 
Effects of this medicine
This medicine has a long bronchodilator effect by a muscarinic receptor antagonist action. This will help relieve symptoms such as breathing difficulty caused by airway obstruction. It is usually used to treat Chronic Obstructive Pulmonary Disease (chronic bronchitis, pulmonary emphysema). It should not be used to relieve a sudden attack that has already begun.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have angle-closure glaucoma, difficulty in urination due to prostate hypertrophy.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<o be written by a healthcare professional>>
•In general, for adults, inhale one puff at a time, once a day. Strictly follow the instructions.
•Try to inhale this medicine at the same time each day.
•Read the instruction leaflet for users thoroughly before using this medicine.
•To wash away medicine in the mouth and/or throat, gargle after inhaling this medicine. (if you have difficulty gargling, rinse out your mouth.)
•If you miss a dose, inhale a dose as soon as possible. However, do not inhale this medicine more than once a day. You should never take two doses at one time.
•If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
•Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
• Possible adverse reactions to this medicine
The most commonly reported adverse reactions include cough, breathing difficulty, sore throat, upperrespiratory tract infection, and dysphonia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
•palpitation, dizziness, faint [Atrial fibrillation]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
•Discard the remainder. Do not store them.
GlaxoSmithKline K.K.External
Published: 10/2015
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.