英文药名：MILMAG Tablets（Magnesium Hydroxide）

中文药名：氢氧化镁片

生产厂家：Emujifama制药

ミルマグ錠３５０ｍｇ

治疗类别名称
抗酸
缓泻剂
药理作用 
本品为氧化镁水解而成的氢氧化镁乳剂，由于分散度大，抗酸作用强而迅速，且与胃酸作用时无二氧化碳生成，故服用时较舒适。大剂量服用时有轻泻作用。
适应证
用于便秘、胃及十二指肠溃疡。
○抗酸剂
每日数次0.9-2.4克。此外，增加或减少取决于患者的年龄和症状。
○泻药使用
成人，分每天一次口服给药至0.9-2.1克需要的基础或多次。此外，增加或减少取决于患者的年龄和症状。
包装规格
片：350mg
PTP 100粒
PTP 1000片
瓶 1000片
制造厂商
Emujifama有限公司

注：使用以原处方为准：http://www.info.pmda.go.jp/go/pack/2344003F1038_1_02/
Efficiency classification name
Antacid
Laxative agent
Brand Name
Mirumagu tablets 350mg
composition
Component-content
One tablet in the magnesium hydroxide 0.35g
Additive
Corn starch, white sugar, non-fat dry milk (casein-containing), talc, sodium saccharin hydrate, l-menthol, perfume, propylene glycol
Contraindication
Patients for the milk it is allergic (. Containing casein as this drug additive)
Efficacy or effect
Improvement of antacid action and symptoms in
○ following disease
Stomach and duodenal ulcer, gastritis (steep, including chronic gastritis, the drug-induced gastritis), upper gastrointestinal dysfunction (neurogenic anorexia vibration, so-called gastroptosis disease, including the gastric hyperacidity)
○ constipation disease
If you want to use as
○ antacid
As magnesium hydroxide, usually, adult, divided oral administration in several times a day 0.9~2.4g. It should be noted that, to increase or decrease depending on the patient's age and symptoms.
If you want to use as a laxative
○As magnesium hydroxide, usually, adult, split orally administer the daily 0.9~2.1g to needed basis or for several times. It should be noted that, to increase or decrease depending on the patient's age and symptoms.
This drug is for saline laxative, when administered as a laxative, as much water as possible - which is usually more effective to drink about 180mL-.
Careful administration
Patients with renal failure
[Excretion of magnesium is inhibited there is a risk of the reservoir]
Patients with cardiac dysfunction
[There is a risk of bradycardia]
Patients with diarrhea
[So slow there is under the action, there is a fear that worsen the diarrhea]
Patients hypermagnesemia
[Which may worsen the symptoms.]
Pharmacology
Antacid action 1-2)
Magnesium hydroxide to neutralize the hydrochloric acid in the stomach, indicating the antacid action. At this time, since not generate carbon dioxide gas, without stimulating the stomach wall, less susceptible to secondary gastric acid secretion.
Laxative action 1-2)
After the magnesium hydroxide became magnesium chloride by neutralization reaction in the stomach, reacted with sodium bicarbonate in the intestine soluble, it becomes heavy magnesium carbonate or magnesium carbonate poorly absorbed. By depriving the water from the intestinal wall to maintain isotonic osmotic pressure of the intestinal cavity fluid, intestinal contents is enormous to retain moisture, softening and, to reach the large intestine to enhance peristalsis Yuruka action It is shown. No direct stimulatory effect of the drug into the intestinal mucosa.
Physicochemical knowledge of active ingredient
Generic name
Magnesium hydroxide
Chemical name
Magnesium Hydroxide
Molecular formula
Mg (OH) 2
Molecular weight
58.32
Behavior
Magnesium hydroxide is a white powder, there is no smell. Practically insoluble in water or ethanol (95). Soluble in dilute hydrochloric acid.