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Ganaton Tablets(盐酸伊托必利片)

2016-09-30 08:08:07  作者:新特药房  来源:互联网  浏览次数:27  文字大小:【】【】【
简介: 英文药名:Ganaton(Itopride Hydrochloride Tablets) 中文药名:盐酸伊托必利片 生产厂家:安斯泰来制药 ガナトン錠50mg 治疗类别名称肠胃蠕动激活商標名 Ganaton Tablets 50mg 一般名イトプリド ...

英文药名:Ganaton(Itopride Hydrochloride Tablets)

中文药名:盐酸伊托必利片

生产厂家:安斯泰来制药

ガナトン錠50mg

治疗类别名称
肠胃蠕动激活
商標名
Ganaton Tablets 50mg
一般名
イトプリド塩酸塩(Itopride Hydrochloride)
化学名
N-[4-[2-(Dimethylamino)ethoxy]benzyl]-3,4-dimethoxybenzamide monohydrochloride
構造式

分子式
C20H26N2O4・HCl
分子量
394.89
性状
白色至淡黄白色结晶或结晶性粉末,不臭,味微苦。
非常易溶于水,易溶于甲醇或乙酸(100),微溶于乙醇(95),和在乙酸酐或乙醚几乎不溶。水性溶液(1→10)的pH值是从4.0至5.0。
熔点
193〜198℃
分配系数
5.7[pH7.4,1-辛醇/缓冲]
药效药理
1. 作用机序
Ganaton促进通过多巴胺D2受体拮抗作用释放的乙酰胆碱,并且还具有乙酰胆碱酯酶抑制作用,抑制被释放的乙酰胆碱的降解。这些合作行动表明胃肠的蠕动促进作用。
2. 肠胃蠕动激活作用
(1) 胃肠蠕动增强
并以剂量依赖性方式增强胃肠蠕动清醒。
(2) 胃内容物排空增强
加强胃排空功能的影响
3. 呕吐放松
剂量依赖性方式抑制狗的阿朴吗啡诱发的呕吐。
适应病症
慢性胃炎胃肠道症状(腹胀,上腹痛,食欲不振,胃灼热,恶心,呕吐)
用法用量
口服施用之前粗粉被分成每天注射150毫克作为成人伊托必利盐酸盐三次。
此外,这取决于患者的年龄和症状。
包装规格
PTP:100片(10片×10),1000片(10片×100),2100片(21片×100),3000片(10片×300)瓶:1000片


制造厂商
安斯泰来制药公司
完整处方来源:http://www.info.pmda.go.jp/go/pack/2399008F1020_6_01/
Ganaton Tablets(Itopride hydrochloride)
Ganaton Tablets 50mg(ガナトン錠50mg)
Brand name : Ganaton Tablets 50mg
 Active ingredient: Itopride hydrochloride
 Dosage form: white tablet with split line on one side, diameter: approx. 7.3mm, thickness: approx. 3.1mm
 Print on wrapping: (Face) house-mark, HC803, ガナトン50mg, (Back) house-mark, HC803, ガナトン50mg, 消化管運動賦活剤, イトプリド(Itopride)
Effects of this medicine
This medicine promotes release of acetylcholine and controls degradation of acetylcholine to stimulate gastrointestinal motility.
It is usually used to improve gastrointestinal symptoms (abdomen enlarged feeling, upper abdominal pain, loss of appetite, heartburn, nausea and vomiting) in chronic gastritis.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•In general, for adults, take 1 tablet (50 mg of the active ingredient) at a time, three times a day, before meals. The dosage may be decreased according to the age or symptoms. Strictly follow the instructions.
•If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
•If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
•Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
• Possible adverse reactions to this medicine
The most commonly reported adverse reactions include rash, redness, itch, diarrhea, abdominal pain, constipation and headache. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
•facial pallor, cold sweat, dizziness on standing up  [shock, anaphylaxis]
•general malaise, loss of appetite, yellowing of the skin and the white of eyes  [hepatic function disorder, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
•Discard the remainder. Do not store them. 
Astellas Pharama Inc.Internal
Revised: 1/2016
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.

责任编辑:admin


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