部分中文DANTRIUM处方资料（仅供参考）

中文别名：1-[[[5-(4-硝基苯)-2-呋喃亚甲基]氨基]-2,4-咪唑烷二酮钠盐;
英文名称：dantrolene sodium
英文别名：Dantrolene, Sodium Salt;1-[[5-(p-Nitrophenyl)furfurylidene]amino]-hydantoin sodium salt; 1-[5-(-4-Nitrophenyl)furfurylideneamino]imidazolidine-2,4-dione sodium;
中文名称：丹曲林钠
产品英文名称：Dantrolene Sodium
功效主治：用于各种原因引起的上运动神经元损伤所遗留的痉挛性肌张力增高状态，如脑卒中、脑外伤、脊髓损伤、脑性瘫痪、多发性脑血管硬化等。

药理作用：丹曲林钠是一种直接作用于骨骼肌的肌松剂。其主要作用部位是骨骼肌的肌浆网，通过抑制肌浆网释放钙离子而减弱肌肉收缩。

不良反应：可能出现肌无力、嗜睡、头晕目眩、疲劳不适、腹泻，罕见的有心动过速、血压不稳、胸腔积液、心包炎、血尿、排尿障碍等，必要时需停药。长期使用可能引起肝肾功能损害。

禁忌症：
1、对本品过敏者。
2、肝肾功能障碍。
3、功能性痉挛状态。
4、关节病变及外伤后肌痉挛。
5、35岁以上及应用雌激素的妇女。

用法用量：口服：应在医师指导下应用，一般情况下，起始量可用25mg，一日1次，以后每周逐渐增加，最高至50mg，一日3次。

贮藏方法：密封，在干燥处保存。

注意事项：
1、服药期间应定期检查肝肾功能。
2、有心血管、呼吸系统疾病及肝病史慎用。

GENERIC NAME: DANTROLENE - ORAL (DAN-trow-leen)

BRAND NAME(S): Dantrium

WARNING: Infrequently, dantrolene may cause serious (sometimes fatal) liver problems. The risk is greater when using larger amounts (over 800mg/day) of dantrolene. This risk also appears to be greater in women, in people over 35 years of age, and in those people using other medications at the same time. To minimize the possibility of getting liver problems from this medication, your doctor will monitor you and test for liver conditions. Promptly notify your doctor if you have signs of liver problems such as yellowing of the eyes or skin, dark urine, severe stomach or abdominal pain, or unusual fatigue. Do not take more dantrolene than prescribed. If there is no noticeable improvement in your condition after 45 days of use, your doctor must be notified and dantrolene should be stopped.

USES: Dantrolene relaxes muscles and relieves pain and discomfort associated with muscle spasms due to certain nerve disorders such as multiple sclerosis or spinal cord injuries or may be given for special cases of high fever.

OTHER USES: This medication may also be used for muscle pain due to exercise or for heat stroke due to medications which decrease sweating.

HOW TO USE: Take this drug exactly as directed by your doctor. The dosage will be adjusted for maximum benefit and minimal side effects. Follow your doctor's directions carefully. Do not increase your dose or take it more often than prescribed. Do not suddenly stop taking this drug without your doctor's approval.

SIDE EFFECTS: May cause drowsiness, dizziness, weakness, tiredness or diarrhea. If these effects persist or worsen, notify your doctor. Notify your doctor promptly if you develop any of the following signs: liver problems (e.g., yellowing of your eyes or skin). Unlikely to occur but report any of the following symptoms to your doctor: constipation, black or tarry stools, nausea, vomiting, abdominal pain, headache, seizure, heart palpitations, loss of appetite, confusion, depression, increase in urination, sensitivity to sunlight. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Before using this drug, tell your doctor your medical history especially of: liver or heart disease, breathing problems, any drug allergies. Because this drug may cause dizziness and/or drowsiness, use caution when driving or performing tasks that require alertness. Avoid alcohol consumption as it may increase the drowsiness and/or dizziness effects of this drug. Because this drug may increase your sensitivity to sunlight, limit your exposure to the sun. You may need to use a sunscreen and wear protective clothing. This drug should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. The manufacturer of this drug states this drug should not be used by nursing women.

DRUG INTERACTIONS: Tell your doctor of all over-the-counter or prescription medication you may use including: sedatives, tranquilizers, narcotic pain relievers, sleeping pills, seizure medication, muscle relaxants, medications for depression, drugs that may affect the liver (e.g., long-term acetaminophen use, certain anti-cancer drugs). Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

NOTES: Do not allow anyone else to use this medication. This drug may affect certain blood tests. Make sure you inform all your healthcare providers you use this drug.

MISSED DOSE: If you miss a dose, take it as soon as remembered if it is within an hour or so. If you do not remember until later, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

STORAGE: Store at room temperature between 59 and 86 degrees F (between 15 and 30 degrees C) away from moisture and heat. Do not store in the bathroom.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).
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产地国家: 美国
所属类别: 骨科药物->骨骼肌松弛药
原产地英文商品名:
DANTROLENE SODIUM(DANTRIUM GENERIC) 20mg/vial 6vials/case
原产地英文药品名:
DANTROLENE SODIUM
原产地英文化合物名称:
1-[5-(-4-Nitrophenyl)furfurylideneamino]imidazolidine-2,4-dione sodium
中文参考商品译名:
丹曲林钠(DANTRIUM仿制药) 20毫克/瓶 6瓶/盒
中文参考药品译名:
丹曲林钠
中文参考化合物名称:
1-[[[5-(4-硝基苯)-2-呋喃亚甲基]氨基]-2,4-咪唑烷二酮钠盐
生产厂家中文参考译名:
US WORLD MEDS
生产厂家英文名:
US WORLD MEDS