英文药名: Orthovisc(Sodium Hyaluronate)

中文药名: 透明质酸钠注射剂

生产厂家: Ortho Biotech Products

Description

Orthovisc® (sodium hyaluronate) reduces joint pain and improves joint mobility providing significant relief from the pain of osteoarthritis (OA) of the knee. Orthovisc® supplements the synovial fluid to naturally augment lubrication, cushioning and offer protection to the arthritic knee joint.
Orthovisc® is injected using a simple procedure called viscsupplementation. The procedure is performed by an orthopaedic surgeon, rheumatologist, or other qualified health professional. The doctor prepares the patient's knee with a local anesthetic, then injects Orthovisc® directly into the knee joint where it combines with the synovial fluid. Orthovisc® acts only in the knee joints, so it will not interfere with any other medications the patient is taking.
For many patients, relief of osteoarthritic discomfort begins immediately. Full benefit is achieved after three simple treatments given at weekly intervals. For optimal results to be realized it is important to receive all three treatments.
Significant pain reduction from OA of the knee can last up to 6 months. Patients will enjoy enhanced joint mobility and joint protection. Patients will be able to resume many of the activities they once enjoyed.
ORTHOVISC® is a sterile, non-pyrogenic solution of sodium hyaluronate for intra-articular injection.

ORTHOVISC® contains 15mg/ml of sodium hyaluronate (NaHA) dissolved in physiological saline. The kinematic viscosity of the solution is adjusted to 20,000-50,000 centistokes, and its osmolality is approximately 340 milliosmoles.

Sodium hyaluronate is a high molecular weight polysaccharide composed of sodium glucuronate and N-acetylglucosamine. Sodium hyaluronate is ubiquitously distributed throughout the tissues of the body and is present in high concentrations in such tissues as vitreous humor, synovial fluid, umbilical cord and dermis. Sodium hyaluronate functions as a tissue lubricant(*1,2) and is thought to play an important role in modulating the interactions between adjacent tissues. It can also act as a viscoelastic support maintaining a separation between tissues. Different sodium hyaluronate preparations may have different molecular weights, but are thought to have the same chemical structure. The sodium hyaluronate in ORTHOVISC®(*3) has an average molecular weight greater than one million daltons. ORTHOVISC® is non-inflammatory and non-pyrogenic. Sodium hyaluronate preparations have been shown to be well tolerated in human eyes(*4), non-antigenic(*5,6) and do not interfere with normal wound healing processes. The sodium hyaluronate in ORTHOVISC® is extracted from a natural avian source.

INDICATIONS: 
ORTHOVISC® is indicated as a viscoelastic supplement or a replacement for synovial fluid in human joints. ORTHOVISC® is well suited for treatment of the symptoms of human synovial joint dysfuntions such as osteoarthritis(*7). The actions of ORTHOVISC® are lubrication and mechanical support.

规格：

1% 2ml/支/盒