部分中文Protonix处方资料（仅供参考）
药物名称：泮托拉唑钠
药理作用：
通过特异性地作用于胃粘膜壁细胞，降低壁细胞中的H+-K+-ATP酶的活性，从而抑制了胃酸的分泌；与奥美拉唑和兰索拉唑相比，本品对细胞色素P450依赖性酶的抑制作用较弱。
适应症：
适用于活动性消化性溃疡（胃、十二指肠溃疡），反流性食管炎和卓-艾氏综合征。
用法与用量：
十二指肠溃疡，胃溃疡和反流性食管炎，每日早晨口服一片。十二指肠溃疡疗程通常为2～4周，胃溃疡和反流性食管炎疗程通常为4～8周。
不良反应：
临床应用偶有头晕、失眠、嗜睡、恶心、腹泻和便秘、皮疹、肌肉疼痛等症状。
禁忌症：
1.哺乳期妇女及妊娠头三个月妇女禁用。
2.对本品过敏者禁用。
注意事项：
1.大剂量使用时可出现心律不齐，转氨酶增高，肾功能改变，粒细胞降低等。
2.本品为肠溶制剂，服用时请勿咀嚼。
3.当怀疑胃溃疡时，应首先排除癌症的可能性。因为本品治疗可减轻其症状，从而延误诊断。
4.儿童用药的疗效及安全性资料尚未建立。
5.肝肾功能不全者慎用。
贮藏：
遮光，密封，在凉暗处保存。
What is Protonix?
Protonix is in a group of drugs called proton pump inhibitors.
It decreases the amount of acid produced in the stomach.
Protonix is used to treat erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excess stomach acid such as Zollinger-Ellison syndrome.
Protonix may also be used for purposes other than those listed in this medication guide.
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Important information about Protonix
Do not stop taking Protonix even if you begin to feel better. Your symptoms may improve before the condition is fully treated. Do not crush, chew, or break a delayed-release (enteric-coated) tablet.
It is specially made to release the medicine slowly into your body.
The oral granules should be mixed only with applesauce or apple juice to make swallowing easy. Do not use any other type of liquid or soft food. Protonix granules may also be given with apple juice through a nasogastric (NG ) tube.
Some conditions must be treated long-term with Protonix. The chronic use of Protonix has caused stomach cancer in animal studies, but it is not known if Protonix would have the same effects in humans. Talk with your doctor about your specific risk of developing stomach cancer.
Long-term treatment with Protonix may also make it harder for your body to absorb vitamin B-12, resulting in a deficiency of this vitamin. Talk with your doctor if you need long-term Protonix treatment and you have concerns about vitamin B-12 deficiency.
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What should I discuss with my healthcare provider before taking Protonix?
Do not take Protonix if you are allergic to pantoprazole. Before taking Protonix, tell your doctor if you are allergic to any drugs.
Some conditions must be treated long-term with Protonix. The chronic use of Protonix has caused stomach cancer in animal studies, but it is not known if this medication would have the same effects in humans. Talk with your doctor about your specific risk of developing stomach cancer.
Long-term treatment with Protonix may also make it harder for your body to absorb vitamin B-12, resulting in a deficiency of this vitamin. Symptoms of a vitamin B-12 deficiency may develop slowly and include pale skin, weakness, tired feeling, shortness of breath, and a fast heart rate. Talk with your doctor if you need long-term Protonix treatment and you have concerns about vitamin B-12 deficiency.
FDA pregnancy category B. Protonix is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Pantoprazole can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
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How should I take Protonix?
Take Protonix exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Protonix tablets can be taken with or without food.
Protonix oral granules should be taken 30 minutes before a meal. Do not crush, chew, or break the tablet. Swallow the tablet whole. The enteric-coated tablet has a special coating to protect your stomach.
Breaking the tablet could damage this coating, causing too much of the drug to be released at one time.
The oral granules should be mixed only with applesauce or apple juice to make swallowing easy. Do not use any other type of liquid or soft food. Sprinkle the granules directly onto a teaspoon of applesauce and swallow this mixture right away without chewing. Or pour the granules into a cup with 1 teaspoon of apple juice, stir for 5 seconds and swallow right away. To make sure you get the entire dose, add a little more apple juice to the same glass, swirl
gently and drink right away. Do not save the granule mixture for later use.
To give Protonix granules through a nasogastric (NG) feeding tube:Attach a 60-milliliter syringe to the NG tube and remove the plunger. Hold the syringe high enough to prevent any bends in the tube.
Sprinkle the Protonix granules into the syringe barrel and mix in 2 teaspoons of apple juice. Gently tap or shake the syringe as it empties into the tube.
Add another 2 teaspoons of apple juice to the syringe to help rinse the granules through and to make sure the entire Protonix dose is given. Tap or shake the syringe as the juice empties into the tube.
Repeat the rinse with 2 teaspoons of apple sauce at least twice more, gently shaking the syringe as it empties into the tube. Make sure there are no granules remaining in the syringe or NG tube.
Do not stop taking Protonix even if you begin to feel better. Your symptoms may improve before the condition is fully treated. Call your doctor if your condition does not improve after 8 weeks of treatment. Store Protonix at room temperature away from moisture and heat.
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What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time.
Do not take extra medicine to make up the missed dose.
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What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Protonix is not expected to produce life-threatening symptoms.
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What should I avoid while taking Protonix?
Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using Protonix.
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Protonix side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects are more likely to occur, such as:nausea, vomiting;gas, stomach pain;diarrhea; orheadache.
Side effects other than those listed here may also occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Protonix side effects in more detail
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What other drugs will affect Protonix?
Before taking Protonix, tell your doctor if you are using any of the following drugs:ampicillin (Omnipen, Principen);atazanavir (Reyataz);a blood thinner such as warfarin (Coumadin);clopidogrel (Plavix);ketoconazole (Nizoral); or iron (Feosol, Mol-Iron, Fergon, Femiron, others).
This list is not complete and there may be other drugs that can interact with Protonix. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
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Where can I get more information?
Your pharmacist can provide more information about Protonix.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient.
Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If younurse or pharmacist.
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产地国家: 美国
原产地英文商品名:
PROTONIX SUSPENSION 40mg/packet 30packets/box
原产地英文药品名:
PANTOPRAZOLE SODIUM
中文参考商品译名:
PROTONIX混悬剂 40毫克/包 30包/盒
中文参考药品译名:
泮托拉唑钠
生产厂家中文参考译名:
惠氏
生产厂家英文名:
WYETH PHARMS INC