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BARNETIL Tablets(盐酸舒必利片)

2016-06-18 06:02:13  作者:新特药房  来源:互联网  浏览次数:0  文字大小:【】【】【
简介: 英文药名:BARNETIL Tablets(Sultopride hydrochloride) 中文药名:盐酸舒必利片 生产厂家:拜耳药品制药 バルネチール錠50/バルネチール錠100/バルネチール錠200 治疗类别名称苯甲酰胺抗精神 ...

英文药名:BARNETIL Tablets(Sultopride hydrochloride)

中文药名:盐酸舒必利片

生产厂家:拜耳药品制药

バルネチール錠50/バルネチール錠100/バルネチール錠200

治疗类别名称
苯甲酰胺抗精神病药
商標名
BARNETIL
構造式

一般名
スルトプリド塩酸塩(Sultopride Hydrochloride)
化学名
(±)-N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-ethylsulfonyl-o-anisamide hydrochloride
分子式
C17H26N2O4S・HCl
分子量
390.93
性状
本品为白色或奥比淡黄色粉末。
此产品可溶于水,微溶于甲醇或乙酸(100),乙醇(95)中微溶,难以非常易溶于乙酸酐。
本产品(1→10)的水溶液呈无旋光。
操作注意事项
您将被要求保持他们在儿童接触不到的地方。
适应病症
狂躁,兴奋和幻觉,妄想精神分裂症的状态
用法用量
成人:每天口服300-600毫克给药。该剂量可以根据年龄和症状进行调整,但可提高1天1800mg。
药效药理
1. 药理作用
(1) 药理学的抗阿朴吗啡作用,抗甲基苯丙胺作用显示(鼠),另外,在外围,将其作为指标来对阿朴吗啡诱发的呕吐(狗)的抑制作用和瞬膜的收缩反应的抗多巴胺作用(猫)是均高于氟哌啶醇和舒必利更强。
(2) 在体外,虽然神经化学增强多巴胺的营业额,与氟哌啶醇和氯丙嗪,它不作用于多巴胺敏感腺苷酸环化酶。
2. 作用机序
抗精神病药物的作用机制,推测其密切相关的抗多巴胺作用,也通过行为药理学方法和神经化学方法,这种药物观察到中部展示效果抗多巴胺是的。
包装规格
片剂
PTP包装

50毫克: 100片(10片×10)1000片


100毫克:100片(10片×10)1000片


200毫克:100片(10片×10),1000片(10片×100)1000片


制造厂商
拜耳药品社有限公司[联盟]住友制药有限公司
完整处方资料附件:http://www.info.pmda.go.jp/go/pack/1179032C1046_2_10/
BARNETIL Tablets(Sultopride hydrochloride)
BARNETIL Tablets 50(バルネチール錠50)
Brand name : BARNETIL Tablets 50
 Active ingredient: Sultopride hydrochloride
 Dosage form: white tablet, diameter: 5.6 mm, thickness: 2.8 mm
 Print on wrapping: (face) MPI 130 50 mg (back) バルネチール50 mg
BARNETIL Tablets 100(バルネチール錠100)
Brand name : BARNETIL Tablets 100
 Active ingredient: Sultopride hydrochloride
 Dosage form: white tablet, diameter: 7.1 mm, thickness: 3.4 mm
 Print on wrapping: (face) MPI 131 100 mg (back) バルネチール100 mg
BARNETIL Tablets 200(バルネチール錠200) 
Brand name : BARNETIL Tablets 200
 Active ingredient: Sultopride hydrochloride
 Dosage form: white tablet, diameter: 9.1 mm, thickness: 4.2 mm
 Print on wrapping: (face) MPI 132 200 mg (back) バルネチール200 mg
Effects of this medicine
This medicine inhibits the actions of neurotransmitters (dopamine) in the brain and stabilizes mood.
It is usually used to treat mania and schizophrenia.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have heart failure, Parkinson's disease or prolactin-secreting pituitary tumor.
If you are suspected of having brain disorders (encephalitis, brain tumor, aftereffects of head injury, etc.).
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<        to be written by a healthcare professional>>
•In general, for adults, take 300 to 600 mg as sultopride in several divided doses a day. The dosage may be adjusted according to your disease, age or symptoms. However, the maximum daily dose is 1,800 mg. This medicine includes 200 mg of sultopride in a tablet. Strictly follow the instructions.
•If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
•If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
•Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
•Do not drive, work at heights, or operate dangerous machinery, as this medicine may cause sleepiness or decrease of attention and concentration.
•The antiemetic effect of this medicine may mask vomiting symptoms due to poisoning caused by other medicine.
•Pay attention when you drink alcohol because alcohol may intensify the medical effects.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include tremor (shivering limbs), akathisia (motor anxiety and paresthesia), extrapyramidal symptoms such as muscle stiffness, sleepiness/somnolence, rash, itching sensation and liver disorder. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
•muscle rigidity, swallowing difficulty, tachycardia, blood pressure changes, sweating  [malignant syndrome]
•loss of appetite, nausea/vomiting, severe constipation  [paralytic ileus]
•convulsions  [ convulsion]
•constant involuntary movement of the face, particularly around the mouth  [delayed dyskinesia]
•palpitation, shortness of breath, disturbed pulse  [QT prolongation, ventricular tachycardia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
•Discard the remainder. Do not store them. Consult with your dispensing pharmacy or medical institution how to discard the medicine.
Sumitomo Dainippon Pharma Co.,Ltd.Internal
Revised: 12/2014
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.

责任编辑:admin


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