英文药名：Laxoberon Solution 0.75%（Sodium Picosulfate Hydrate）

中文药名：匹可硫酸钠溶液0.75％

日文药名：ラキソベロン内用液0.75%

生产厂家：帝人制药
类别名称
滴型通便剤，结肠检查治疗前，润肠通便剤
商標名
*Laxoberon Solution 0.75%
一般名
ピコスルファートナトリウム水和物（Sodium Picosulfate Hydrate）
化学名
Disodium 4,4'-(pyridin-2-ylmethylene)bis(phenyl sulfate)monohydrate
化学構造式

分子式
C18H13NNa2O8S2・H2O
分子量
499.42
性状
白色结晶性粉末，无臭，味。这是非常易溶于水，略溶于甲醇，微溶于乙醇（99.5），并在乙醚中几乎不溶。渐渐地，彩色光。
药效药理
匹酸钠水合物，胃，小肠中的影响很小，它是通过从结肠菌群酶芳基硫酸酯酶，活性（大鼠）的二酚水解。二酚体示出了泻下作用于肠粘膜以下的效果。
(1) 加强肠道蠕动的作用
(2) 吸湿抑制作用
适应症
便秘症(排便疼痛)
用法用量
1. 各种便秘症
通常情况下，10-15天为成人（0.67〜为1.0mL）口服一次。
孩子每天一次，在下列标准口服给药。此外，想增加或减少取决于患者的年龄和症状。
6月龄以下几点：2滴（0.13mL）
年龄7-12个月：3滴（0.20mL）
年龄1-3岁：6滴（0.40mL）
年龄4-6岁：7滴（0.46mL）
年龄7-15岁：10滴（0.67mL
2.术后排便辅助
通常情况下，10-15天为成人（0.67〜为1.0mL）口服降一次。此外，想增加或减少取决于患者的年龄，症状。
3. 排便促进造影剂（硫酸钡）给药后
通常，6-15下降到成年人（0.40〜为1.0mL）予口服给药。此外，想增加或减少取决于患者的年龄和症状。
4. **消除肠内容物在手术前
**正常，14滴为成人（0.93mL）予口服给药。此外，想增加或减少取决于患者的年龄和症状。
5. 消除处理前在大肠检查肠内容物（X射线，内窥镜检查）
通常情况下，20毫升口服给药试验计划时间为成人10至15小时之前。此外，想增加或减少取决于患者的年龄和症状。
包装规格
1）滴型
10毫升×10（定量降落型遮光密闭容器）
10毫升×12（单位剂量容器包装铝在内）
100毫升（棕色玻璃瓶）

在100毫升的包装（褐色玻璃瓶），附加一个校准滴管（液滴数的规模和毫升显示定量滴下类型的容器而言）。
2）片剂
PTP
100片（10片×10），500片（10片×50），1000片（10片×100）
瓶子

1000片（棕色玻璃瓶）
生产厂商
帝人制药有限公司
完整处方资料附件：
滴型：http://www.info.pmda.go.jp/go/pack/2359005S1240_1_04/
片剂：http://www.kegg.jp/medicus-bin/japic_med?japic_code=00057668
Laxoberon Solution 0.75%
Brand name : Laxoberon Solution 0.75% [For constipations, etc.]
　Active ingredient: Sodium picosulfate hydrate
　Dosage form: colorless to light yellow oral solution
　Print on wrapping: 
Effects of this medicine
This medicine turns into active form by being degraded by bacteria in the large intestine. It enhances bowl peristalsis and inhibits water absorption to show cathartic action.
It is usually used for constipations, for support of postoperative defecation, for stimulation of defecation after administration of contrast agent (barium sulfate) and for elimination of intestinal contents before surgery.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you are suspected of acute abdomen (with abdominal pain).
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<        to be written by a healthcare professional>>
•For constipations: In general, for adults, take 10 to 15 drops (0.67 to 1.0 mL, 5 to 7.5 mg of the active ingredient) at a time, once a day. For children aged 6 months or younger, take 2 drops (0.13 mL); 7 to 12 months, 3 drops (0.20 mL); 1 to 3 years, 6 drops (0.40 mL); 4 to 6 years, 7 drops (0.46 mL); 7 to 15 years, 10 drops (0.67 mL) at a time, once a day.
For support of postoperative defecation: In general, for adults, take 10 to 15 drops (0.67 to 1.0 mL, 5 to 7.5 mg of the active ingredient) at a time, once a day.
For stimulation of defecation after administration of contrast agent (barium sulfate): In general, for adults, take 6 to 15 drops (0.40 to 1.0 mL, 3 to 7.5 mg of the active ingredient).
For elimination of intestinal contents before surgery: In general, for adults, take 14 drops (0.93 mL, 7.0 mg of the active ingredient).
The dosage may be adjusted according to your age and symptoms in any case. Strictly follow the instructions.
•Drop appropriate amount of solution into a glass of water and drink it. If you have no defecation or become diarrhetic with instructed dosage, consult with your doctor or pharmacist.
•Do not apply this medicine to your eyes. If the medicine accidentally gets into the eye, wash the eye with running water well immediately. If you notice any abnormality, visit your doctor or ophthalmologist.
•If you miss a dose, for constipations, skip the missed dose and continue your regular dosing schedule from the next day. For support of postoperative defecation and for stimulation of defecation after administration of contrast agent, follow the instructions of your doctor. You should never take two doses at one time.
•If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
•Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
• Possible adverse reactions to this medicine
The most commonly reported adverse reactions include abdominal pain, borborygmus, nausea/vomiting, hives or rash. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
No pertinent entries.
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
•Discard the remainder. Do not store them.
TEIJIN PHARMA LIMITEDInternal
Revised: 8/2014
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.