部份中文沐舒坦处方资料(仅供参考) 药品英文名 Ambroxol 药品别名 安布索、溴环己胺醇、氨溴醇、胺溴素、美舒咳、沐舒痰、沐舒坦、痰之保克、兰勃素缓释胶囊、Brovanexine、Mucosolvan、Lanbroxol、Lasolvan 药物剂型 1.片剂:30mg; 2.溶液剂:30mg(5ml); 3.注射剂:15mg(2ml)。 药理作用 本品为呼吸道润滑祛痰药,为溴己新的第8个代谢产物,能促使呼吸道表面活性物质的形成,调节浆液性与黏液性物质的分泌,增加中性黏多糖分泌,减少酸性黏多糖合成,并促进代谢,使呼吸道黏液理化趋于正常,利于排出。实验证实,用药后,可使痰黏度下降50%。还可改善纤毛运动,增强呼吸道的消除作用。 药动学 口服后胃肠吸收良好,作用迅速,0.5~3h血药浓度达峰值,作用持续达9~10h,35%~50%进入肠肝循环,亦即吸收后经由肝脏代谢,代谢物又经胆道排入小肠,于小肠中再水解成溴环己胺醇,再次被吸收。本药从血液向组织的分布迅速且显著,肺、肝、肾分布较多,其他组织分布较少。血浆蛋白结合率约90%。本品主要通过肝代谢,72h可完全由尿排出。血浆t1/2为4~5h。 适应证 用于各种原因引起痰黏不易咳出者,如急慢性支气管炎、支气管扩张、支气管哮喘、肺结核、术后咳痰困难等。 禁忌证 1.妊娠妇女禁用。 2.哺乳期妇女禁用。 3.青光眼患者禁用。 注意事项 注射剂不宜与pH值大于6.3的其他溶液混合。出现过敏反应,如皮疹、荨麻疹、瘙痒感,应立即停药。 不良反应 有轻度胃肠不适,个别有过敏反应。快速静注可引起头痛、腿痛和疲惫感。 用法用量 1.口服: (1)片剂:饭后吞服: ①成人及10岁以上少年儿童,每天3次,每次30mg; ②5~10岁儿童:每天3次,每次15mg; ③长期治疗可减少为每天2次。 (2)溶液剂:成人及12岁以上儿童:每次10ml,用量随年龄递减而减少。应于饭前服。 2.缓慢静注: (1)成人:每次15mg,每天2~3次; (2)儿童:每次7.5mg,分2~3次。 4.静脉滴注:加入葡萄糖、果糖、盐水或林格液内滴注。 药物相应作用 可与抗生素、糖皮质激素及支气管扩张剂等合并使用 Product name Pediatric Mukosoruban syrup 0.3% Main component ambroxol hydrochloride Classification name - Dosage form colorless to pale yellow syrup Pharmaceutical company Teijin Pharma Limited It promotes the secretion of secretions efficacy lungs and airways, and by enhancing the pili movement and easier to put a button. Usually, acute bronchitis, it will be used to expectorant of bronchial asthma. Previous Precautions in using the medicine, itch, there is a fact that out allergy symptoms such as rash. Are pregnant or breastfeeding. Others are using, such as medicine (you can strengthen the effect on each other, so there is also likely to weaken, please note, including OTC drugs and food products in use in the other). DOSAGE AND ADMINISTRATION Normally, infants, children, take by dividing a day 0.3mL / kg three times (0.9mg / kg of the active ingredient). The dosage may be adjusted according to your age and symptoms. Please Strictly follow the dosing instructions given by your doctor. If you forget to drink, when I noticed, please the missed dose as soon as possible. However, if there is next usually is almost time for skipping once, please the missed dose the next regular dosing schedule. Do not take two doses at once. Please consult your doctor or pharmacist if you took too much of this medicine by mistake. Without the doctor's instructions, please do not stop taking the medicine in their own judgment. Notes on life - Side effect The main side effects, stomach discomfort, nausea, stomach pain, abdominal pain, diarrhea, vomiting, (swelling of the face, eyelids, lips) angioedema, rash, urticaria, urticaria-like erythema, and itching has been reported. If you notice these symptoms, please consult your doctor or pharmacist. In rare cases symptoms appear, such as the following, may be the initial symptom of side effects indicated in brackets []. In such cases, discontinue use, please immediately seek medical care. Rash, difficulty breathing, decreased blood pressure [shock, anaphylactoid symptoms] High fever, bloodshot-throat of lip sores, eye pain, red rash to a wide range of skin [mucocutaneous ocular syndrome] Other side effects do not describe all. If you notice any symptoms of concern other than the above came out, please consult your doctor or pharmacist. Storage and other infants, where it is not out of reach of children, please keep in the dark to avoid high temperature, moisture. If you have any left-over medicine, please discard it. http://www.info.pmda.go.jp/go/pack/2239001S1112_1_01/2239001S1112_1_01?view=body#27 http://www.info.pmda.go.jp/go/pack/2239001Q1166_1_01/ ----------------------------------- 产地国家: 日本 原产地英文商品名: Mucosolvan Syrup 0.3% for Pediatric(小児用ムコソルバンシロップ0.3 %)500ml/bottle 原产地英文药品名: Ambroxol Hydrochloride 中文参考商品译名: 沐舒坦口服液(小児用ムコソルバンシロップ0.3 %)500毫升/瓶 中文参考药品译名: 盐酸氨溴索 生产厂家中文参考译名: 帝人制药 生产厂家英文名: Teijin Pharma
--------------------------------------- 产地国家: 日本 原产地英文商品名: Mucosolvan Solution 0.75%(ムコソルバン内用液0.75%)40ml/bottle 原产地英文药品名: Ambroxol Hydrochloride 中文参考商品译名: 沐舒坦口服液0.75%(ムコソルバン内用液0.75%)40毫升/瓶 中文参考药品译名: 盐酸氨溴索 生产厂家中文参考译名: 帝人制药 生产厂家英文名: Teijin Pharma
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